Hydraulic coupling often leads to progressive rock failure accidents.Mechanical tests were performed over a range of combined pore water pressure and confining pressure stress path conditions to study the progressive failure characteristics of sandstone under hydraulic-mechanical coupling and explore the crack initiation and pore water fracture mec

BACKGROUND: Treatment of the complications arising from Prenatal Alcohol Exposure (PAE) has largely been focused on psychosocial and environmental approaches.Research on the use of medications, especially psychotropic medications, has lagged behind.OBJECTIVES: This systematic review sought to investigate psychotropic medication related findings and

Abstract Background The mechanisms by which glia respond to viral central nervous system (CNS) pathogens are now becoming apparent with the demonstration that microglia and astrocytes express an array of pattern recognition receptors that include intracellular RNA and DNA sensors.We have previously demonstrated that glia express Z-DNA binding prote

In recent years, the use of synthetic textile dyes has increased.The effects of these chemicals or their metabolites on our skin and our immune system have not been well studied.However, skin irritants have been reported to break the dermal barrier to start a chain of reactions that dysregulate the immune system.In the last decades, the incidence o